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Pathology

The Department of Pathology

was started in 1986 by Dr. M Balaraman Nair, a renowned pathologist and teacher. It is now headed by Dr.S.Shanthakumari and is the largest department in PSG Medical College. Post graduation in Pathology was started in 2001 with a single seat, which has now been increased to eight admissions per year.

It is a dynamic department with talented and dedicated faculty. The department contributes significantly to the curriculum in medical education and is dedicated to fostering imaginative and talented pathologists who will continue contributing to human well-being in the fundamental efforts of elucidating and understanding disease mechanisms

Contact Information

The Department is organized into 4 major divisions: Histopathology, Cytology, Clinical Pathology and Haematology which includes Transfusion medicine. With an array of facilities that include a museum where over 700 rare and unique specimens are on display, the department aims to develop academic standards of the highest order. The Clinical Pathology and Histopathology Labs are NABL accredited and optimally automated. Accreditation is an external audit of the department’s quality assurance program. Quality control is done by internal and external agencies.

The histopathology laboratory is equipped with a cryostat with which frozen sections are cut. This diagnostic modality helps make quick decisions during surgery on organs such as the breast, brain, intestine etc. In addition, the perinatal division of this section regularly performs fetal autopsies. Currently
Histopathology has updated with automation in all areas of routine.Immunohistochemistry an adjunct test in pathology used for diagnostics and prognosis is fully automated aiding in quicker results.

The cytopathology section examines cells aspirated or exfoliated from various sites. The Papanicolaou (Pap) smear which is a screening investigation done in this section forms an important part of the early screening for cervical cancers. Many types of guided aspirates like ultrasound or CT or endosonographic guided fine needle aspirations are performed here which help to provide rapid, relatively inexpensive and crucial diagnoses.

The clinical pathology laboratory has three major sections – haematology, coagulation and body fluid analysis. This laboratory is equipped with the best in automated equipment like a seven part automated cell counter, fully automated coagulation analyzer and a fully automated urine analyser that provides patients with rapid, accurate and reproducible results. It works round the clock and is accredited by the National Accreditation Board for Testing and Calibration Laboratories (NABL).

Currently the division of Clinical pathology has included flow cytometry which aids the diagnosis of heamtological malignanciess.

The blood bank was established in 1990 and was upgraded to a state of the art components blood bank and regional blood centre in the year 2001. It is recognised as a Regional Transfusion Centre The blood bank is equipped with a vast array of equipment like high speed refrigerated centrifuges, automated blood collection monitors and ultra low temperature freezers.. Transfusion is also provided to renal and liver transplant patients. Besides this the Department offers Aphaeresis services, wherein a particular component is removed from the blood and the remaining fractions of the blood are transfused back into the patient. This will help produce single donor products like single donor platelets and plasma and allow for more frequent donations when compared to whole blood donations. The blood bank encourages auto transfusions, which is a process whereby a patient has the option of being transfused with his own blood that was stored in the bank prior to surgery. This process once again reinforces our philosophy of transfusing safe blood.

The department boasts of a museum that houses almost 1000 speciemens many of which are rare and constitute excellent teaching material.

Research

PG dissertations:

1. “Clinicopathological Spectrum Of Haemophagocytic Syndrome”.
2. “Clinicopathologic Profile Of Biopsy Proven Renal Diseases”.
3. “Immunohistochemical Expression Of Matrix Metalloprotein-2 (Mmp-2) In Inguinal Hernia”.
4. “Histopathological And Immunohistochemical Analysis Of Non-Small Cell Lung Carcinoma With Emphasis On Egfr Expression”.
5. “Study Of The Significance Of Vcs Parameters Generated By The Coulter Lh-780 In Cases Of Lymphocytosis And Monocytosis”
6. “Utility Of Low Hemoglobin Density In The Diagnosis Of Iron Deficiency Anaemia”.
7. “Cd4, Cd8 And Bcl2 Expression In Lichen Planus To Establish The Relationship Between Lymphocytic Exocytosis And Apoptosis”.
8. “The Value Of Microsatellite Instability Testing In Colorectal Polyps”.
9. “Study Of Clot Waveform Analysis In Various Clinical Conditions”.
10. “Clinicopathologic Profile Of Patients Diagnosed With Congenital Disorder Of Hemostasis ”.
11. “Morphometric Analysis Of Crypt Villous Ratio In Tropical Sprue And Its Phenotypical Correlation”.
12. “The Value Of Perinatal Autopsy In The Evaluation Of Genitourinary And Anorectal Malformations ”.
13. “Prognostic Implication Of Survivin Expression In Breast Carcinoma And Correlation With Nottingham Prognostic Index And Ihc4 Score”
14. “Clinicopathological Correlation Of Functional Platelet Disorders”.
15. “Interstitial Lung Disease : Potential Synergy Of Clinical, Radiological And Histopathological Patterns”
16. “Utility Of P16 And Ki67 In Identifying Intraepithelial Lesions Of Endocervix”.
17. “Clinical Utility Of Haematological Parameters In Patient With Acute Coronary Syndrome Visiting The Emergency Department With Acute Chest Pain”.
18. “Utility Of Milan System In Reporting Salivary Gland Cytopathology And Correlation With Histopathological Findings For Risk Stratification”
19. “The Utility Of Perinatal Autopsy In Cns Malformation : A Crosssectional Study In A Tertiary Health Care”.
20. “Magee Equation ; A Potential, Economic Alternative Prognostication Patient With Breast Cancer”
21. “Immunoprofiling Of Biopsies Diagnosed As Inflammatory Bowel Disease”.
22. “Study Of Clinicopathological And Genetic Profile Of Myeloproliferative Disorders”.
23. “Morphological Spectrum And The Value Of Immunohistochemistry In The Evaluation Of Cutaneous Lymphomas And Pseudolymphomas”.
24. “The Role Of Foetal Autopsy In Skeletal Malformations”.
25. “Serum Antiphospho Lipid Antibodies As Prognostic Markers In Patient With Coronary Artery Disease”
26. Monocyte Distribution Width As An Early Indicator Of Sepsis.
27. Ki 67 Expression In Fundic Gland Polyps And Its Correction With Morphology And Phenotypic Features.
28. Clinicopathological Charactersistics And Expressor Patterns (Cmyc & Ebv) Of Large B Cell Lymphoma
29. Hypertensive Disorders Of Pregnancy : Role Of Placental Morphology In Correlation With Angiogenic Anti Angiogenic Factors And Doppler Imaging In Fetal Outcome.
30. Evaluation Of Clinical And Pathological Correlation Of Neoadjucent Chemotherapy In Mastectomy Patients.
31. Serum Antiphospho Lipid Antibodies As Prognostic Markers In Patient With Coronary Artery Disease

Other Research Activities:
1. COCO-HEAL:Cellulose based advanced wound care product made utilizing agro-waste with coconut extract as an antimicrobial agent
2. Third trimester foetal loss: systematic evaluation of placenta and foetal autopsy
3. Amniotic band syndrome: an imperative role of fetal autopsy in pre viable fetuses.
4. Pattern analysis of APTT Clot wave form for detection of Haemostatic changes in sepsis patients –.
5. Clinicomorphological spectrum of qualitative platelet disorders diagnosed using LTA
6. Prediction of Tuberculosis by estimation of pleural fluid protein and sugar using urine dipstick in resource poor settings – A pilot study.
7. Analysis of bacterial contamination in blood bank setting using different donor arm disinfectants and diversion bags
8. Analysis of effectiveness of using microcytic anaemia factor to diagnose iron deficient anaemia in chronic kidney disease patients
9. Analysis of the effectiveness of coagulation assays to diagnose cancer-associated thrombosis in breast cancer patients’

Awards won by faculty/ students :

2022-23

• Dr Ruthra M, Postgraduate in Pathology has been awarded the 1st prize for the poster presentation titled “Utility of Perinatal Autopsy in Foetal Neural Tube defects” in the National Conference on “Molecular Pathology, Updates and Diagnostic challenges on Central Nervous System Tumors, Muscle and Nerve Biopsies” held on 23rd and 24th September 22 at Vinayaka Mission’s Kirupananda Variyar Medical College & Hospital, Salem.

• Dr Selvapriya C, Postgraduate in Pathology has been awarded the 2nd prize for the poster presentation titled “Unravelling the enigma behind peripheral smear and bone marrow plasmacytosis” in the National Conference “Molecular Pathology, Updates and Diagnostic challenges on Central Nervous System Tumors, Muscle and Nerve Biopsies” held on 23rd and 24th September 22 at Vinayaka Mission’s Kirupananda Variyar Medical College & Hospital, Salem.

• Dr S Sakthisankari, Associate Professor guided postgraduate Dr Monica Chandrasekar to present a poster titled “Serological diagnosis of auto immune bullous disorders of skin ,using the BIOCHIP IIF, as a stand alone diagnostic tool of at a CME and Workshop in Immunofluorescence” on March 24th & 25th, 2023 at PSGIMS&R and awarded first prize.

• Dr Ezhil Oviya B, I yr postgraduate was awarded first prize in poster competition in CME on ‘Uterine Pathology’ organized by Govt. Mohan Kumaramangalam Medical College, Salem, on 09.06.23. Poster title : Utility of placental examination in intrauterine infections- Foetal autopsy study – guided by Drs S Pradhiksha D, Asst. Professor and G Umamaheswari, Professor.

• The Indian Association of Pathologists and Microbiologists (IAPM) awarded Dr Sakthisankari Shanmugasundaram with Smt. Kunti Devi Mehrotra Award for the year 2022 for the publication entitled “Pathologists role in identifying cardiac defect – a fetal autopsy series” published in Cardiovascular Pathology 2021 ; March-April 51 : 107312, during the 71st Annual Conference of the IAPM – APCON 2023 held at AIIMS, New Delhi.

Events organized

1. The Department of Pathology, PSG Institute of Medical Sciences & Research, Coimbatore conducted the Annual State Conference TAPCON 2024 from July 4th to 6th ‘24 on behalf of Tamil Nadu and Pondicherry Chapter of Indian Association of Pathologists and Microbiologists. This event started on 4th July 2024 with 5 parallel preconference workshops and 2 days of intense scientific sessions. The speakers are of both national and international repute. Nearly 500 Delegates attended from all southern states.

2. The Department of Pathology conducted a CME on Immunohaematology and Transfusion Medicine on 17th and 18th February 23. It was attended by 70 consultant Pathologists and post graduates from various hospitals, laboratories and medical colleges within and out of Tamilnadu.

3. The Department of Pathology conducted a CME & Workshop in Immunofluorescence in association with TNPC IAPM at PSG IMS&R on 24th and 25th March 2023. It was attended by 140 consultant Pathologists and post graduates from various hospitals, laboratories and medical colleges within and out of Tamilnadu.

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